Dr FRAICHARD Annick

Fiche personne

Coordonnées

UFR-ST UFC
16 route de Gray
25030 BESANCON Cedex

03 81 66 62 54

Territoire

Franche-Comté

Statut

Enseignant-Chercheur

Affiliation

Inserm UMR 1098 "Interaction Hôte-Greffon-Tumeur, Ingénierie Cellulaire et Génique" (Inserm UMR1098 RIGHT)

Université de Franche-Comté (UFC)

Équipes/plateformes

Equipe UMR 1098 - Equipe "Thérapeutique Immuno-Moléculaire des Cancers (TIM-C) - Autophagy, epigenetics and T-cell Immunity in cancer (AETIC)"

Recherche

Expertises :
- Recherche:Biologie Cellulaire
- Recherche:Biologie Moléculaire

Publications

GABARAPL1 Inhibits EMT Signaling through SMAD-Tageted Negative Feedback.

Jacquet M, Hervouet E, Baudu T, Herfs M, Parratte C, Feugeas JP, Perez V, Reynders C, Ancion M, Vigneron M, Baguet A, Guittaut M, Fraichard A, Despouy G

Biology (Basel). 2021 Sep 24;10(10):

The NMD Pathway Regulates mRNA during the EMT.

Baudu T, Parratte C, Perez V, Ancion M, Millevoi S, Hervouet E, Peigney A, Peixoto P, Overs A, Herfs M, Fraichard A, Guittaut M, Baguet A

Biomedicines. 2021 Sep 23;9(10):

The functions of Atg8-family proteins in autophagy and cancer: linked or unrelated?

Jacquet M, Guittaut M, Fraichard A, Despouy G

Autophagy. 2020 Apr 7;:

GABARAPL1 tumor suppressive function is independent of its conjugation to autophagosomes in MCF-7 breast cancer cells.

Poillet-Perez L, Jacquet M, Hervouet E, Gauthier T, Fraichard A, Borg C, Pallandre JR, Gonzalez BJ, Ramdani Y, Boyer-Guittaut M, Delage-Mourroux R, Despouy G

Oncotarget. 2017 Aug;8(34):55998-56020

The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models.

Hervouet E, Claude-Taupin A, Gauthier T, Perez V, Fraichard A, Adami P, Despouy G, Monnien F, Algros MP, Jouvenot M, Delage-Mourroux R, Boyer-Guittaut M

BMC Cancer. 2015 Oct 17;15:729

The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells.

Boyer-Guittaut M, Poillet L, Liang Q, Bole-Richard E, Ouyang X, Benavides GA, Chakrama FZ, Fraichard A, Darley-Usmar VM, Despouy G, Jouvenot M, Delage-Mourroux R, Zhang J

Autophagy. 2014 Jun;10(6):986-1003

Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein.

Seguin-Py S, Lucchi G, Croizier S, Chakrama FZ, Despouy G, Le Grand JN, Ducoroy P, Boireau W, Boyer-Guittaut M, Jouvenot M, Fraichard A, Delage-Mourroux R

Biochimie. 2012 Mar;94(3):748-58

GABARAPL1 antibodies: target one protein, get one free!

Le Grand JN, Chakrama FZ, Seguin-Py S, Fraichard A, Delage-Mourroux R, Jouvenot M, Risold PY, Boyer-Guittaut M

Autophagy. 2011 Nov;7(11):1302-7

GABARAPL1 (GEC1): original or copycat?

Le Grand JN, Chakrama FZ, Seguin-Py S, Fraichard A, Delage-Mourroux R, Jouvenot M, Boyer-Guittaut M

Autophagy. 2011 Oct;7(10):1098-107

GABARAPL1 (GEC1) associates with autophagic vesicles.

Chakrama FZ, Seguin-Py S, Le Grand JN, Fraichard A, Delage-Mourroux R, Despouy G, Perez V, Jouvenot M, Boyer-Guittaut M

Autophagy. 2010 May;6(4):495-505

High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer.

Berthier A, Seguin S, Sasco AJ, Bobin JY, De Laroche G, Datchary J, Saez S, Rodriguez-Lafrasse C, Tolle F, Fraichard A, Boyer-Guittaut M, Jouvenot M, Delage-Mourroux R, Descotes F

Br J Cancer. 2010 Mar 16;102(6):1024-31