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Mots clés : Targeted cancer therapies,Antibody-Drug Conjugates
Publications
INA03, a potent transferrin-competitive antibody-drug conjugate against CD71, for a safer acute leukemia treatment.
Bratti M, Stubbs E, Kolodych S, Souchet H, Kelly L, Merlin J, Marchal M, Castellano R, Josselin E, Pasquer H, Benajiba L, Puissant A, Koniev O, Collette Y, Belanger C, Hermine O, Monteiro RC, Launay P
Mol Cancer Ther. 2024 04 20;:
Reinvestigation of the Automated Synthesis of Stoichiometrically Conjugated Antibodies to Access High Molecular Weight Payloads and Multiplexed Conjugation via an In-Solution Trans-Tagging Process.
Lehot V, Lidický O, Most J, Erb S, Dovgan I, Osypenko A, Koniev O, Kolodych S, Kotrchová L, Chaubet G, Cianférani S, Etrych T, Wagner A
ACS Omega. 2023 10 31;8(43):40508-40516
On the use of DNA as a linker in antibody-drug conjugates: synthesis, stability and in vitro potency.
Dovgan I, Ehkirch A, Lehot V, Kuhn I, Koniev O, Kolodych S, Hentz A, Ripoll M, Ursuegui S, Nothisen M, Cianférani S, Wagner A
Sci Rep. 2020 May 6;10(1):7691
