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Coordonnées
Institut de Recherche sur les Maladies Virales et Hépatiques
3 rue Koeberlé
67000 STRASBOURG
03 68 85 37 06
Statut
Chercheur
Affiliation
Inserm UMR_S 1110 - Institut de Recherche sur les Maladies Virales et Hépatiques (Inserm UMR_S1110)
Équipes/plateformes
Recherche
Expertises :
- Recherche:Virologie
Publications
Hijacking JAKis: JAK inhibitors as potential antiviral molecules, a mini review.
Eber C, Verrier ER
Antiviral Res. 2025 03 27;:106153
[Deciphering the links between hepatic viruses and interferons: molecular interactions and therapeutic implications].
Authier C, Eber C, Fouillé R, Lucifora J, Verrier ER
Virologie (Montrouge). 2025 02 1;29(1):19-39
[Non-alphabetic viral hepatitis].
Pastor F, Delphin M, Lucifora J, Verrier ER
Med Sci (Paris). 2025 02;41(2):145-153
CAM-A-dependent HBV core aggregation induces apoptosis through ANXA1.
Taverniti V, Meiss-Heydmann L, Gadenne C, Vanrusselt H, Kum DB, Giannone F, Pessaux P, Schuster C, Baumert TF, Debing Y, Verrier ER
JHEP Rep. 2024 10;6(10):101134
Major open questions in the hepatitis B and D field - Proceedings of the inaugural International emerging hepatitis B and hepatitis D researchers workshop.
Tu T, Wettengel J, Xia Y, Testoni B, Littlejohn M, Le Bert N, Ebert G, Verrier ER, Tavis JE, Cohen C
Virology. 2024 04 16;595:110089
Comparative analysis of human, rodent and snake deltavirus replication.
Khalfi P, Denis Z, McKellar J, Merolla G, Chavey C, Ursic-Bedoya J, Soppa L, Szirovicza L, Hetzel U, Dufourt J, Leyrat C, Goldmann N, Goto K, Verrier E, Baumert TF, Glebe D, Courgnaud V, Gregoire D, Hepojoki J, Majzoub K
PLoS Pathog. 2024 03 5;20(3):e1012060
JAK1 promotes HDV replication and is a potential target for antiviral therapy.
Heuschkel MJ, Bach C, Meiss-Heydmann L, Gerges E, Felli E, Giannone F, Pessaux P, Schuster C, Lucifora J, Baumert TF, Verrier ER
J Hepatol. 2023 11 2;:
Novel non-HAP class A HBV capsid assembly modulators have distinct and profiles.
Vanrusselt H, Kum DB, Taverniti V, Liu C, Acosta Sanchez A, Corthout N, Munck S, Baumert TF, Beigelman L, Blatt LM, Symons JA, Deval J, Raboisson P, Verrier ER, Jekle A, Vendeville S, Debing Y
J Virol. 2023 09 27;:e0072223
Class a capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation.
Kum DB, Vanrusselt H, Acosta Sanchez A, Taverniti V, Verrier ER, Baumert TF, Liu C, Deval J, Corthout N, Munck S, Beigelman L, Blatt LM, Symons JA, Raboisson P, Jekle A, Vendeville S, Debing Y
Hepatology. 2023 04 28;:
Polymorphisms within DIO2 and GADD45A genes increase the risk of liver disease progression in chronic hepatitis b carriers.
Rybicka M, Verrier ER, Baumert TF, Bielawski KP
Sci Rep. 2023 04 14;13(1):6124
Hepatitis D virus interferes with hepatitis B virus RNA production via interferon-dependent and -independent mechanisms.
Lucifora J, Alfaiate D, Pons C, Michelet M, Ramirez R, Fusil F, Amirache F, Rossi A, Legrand AF, Charles E, Vegna S, Farhat R, Rivoire M, Passot G, Gadot N, Testoni B, Bach C, Baumert TF, Hyrina A, Beran RK, Zoulim F, Boonstra A, Büning H, Verrier ER, Cosset FL, Fletcher SP, Salvetti A, Durantel D
J Hepatol. 2023 01 23;:
Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target.
Verrier ER, Ligat G, Heydmann L, Doernbrack K, Miller J, Maglott-Roth A, Jühling F, El Saghire H, Heuschkel MJ, Fujiwara N, Hsieh SY, Hoshida Y, Root DE, Felli E, Pessaux P, Mukherji A, Mailly L, Schuster C, Brino L, Nassal M, Baumert TF
Gut. 2022 12 9;:
A stable hepatitis D virus-producing cell line for host target and drug discovery.
Bach C, Lucifora J, Delphin M, Heydmann L, Heuschkel MJ, Pons C, Goto K, Scheers E, Schuster C, Durantel D, Pauwels F, Baumert TF, Verrier ER
Antiviral Res. 2022 11 26;209:105477
[Hepatitis B virus receptor: Structure and clinical implications].
Verrier ÉR
Med Sci (Paris). 2022 11;38(11):867-869
Inhibiting cell-to-cell transmission to reach HDV cure: the importance of IFNα.
Lucifora J, Verrier ER, Baumert TF
J Hepatol. 2022 08 8;:
Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences.
Boulahtouf Z, Virzì A, Baumert TF, Verrier ER, Lupberger J
Int J Mol Sci. 2022 Mar 3;23(5):
Capsid Assembly Modulators as Antiviral Agents against HBV: Molecular Mechanisms and Clinical Perspectives.
Taverniti V, Ligat G, Debing Y, Kum DB, Baumert TF, Verrier ER
J Clin Med. 2022 Mar 1;11(5):
Loss of hepatitis D virus infectivity upon farnesyl transferase inhibitor treatment associates with increasing RNA editing rates revealed by a new RT-ddPCR method.
Verrier ER, Salvetti A, Pons C, Michelet M, Rivoire M, Baumert TF, Durantel D, Lucifora J
Antiviral Res. 2022 Jan 17;198:105250
A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery.
Crouchet E, Bandiera S, Fujiwara N, Li S, El Saghire H, Fernández-Vaquero M, Riedl T, Sun X, Hirschfield H, Jühling F, Zhu S, Roehlen N, Ponsolles C, Heydmann L, Saviano A, Qian T, Venkatesh A, Lupberger J, Verrier ER, Sojoodi M, Oudot MA, Duong FHT, Masia R, Wei L, Thumann C, Durand SC, González-Motos V, Heide D, Hetzer J, Nakagawa S, Ono A, Song WM, Higashi T, Sanchez R, Kim RS, Bian CB, Kiani K, Croonenborghs T, Subramanian A, Chung RT, Straub BK, Schuppan D, Ankavay M, Cocquerel L, Schaeffer E, Goossens N, Koh AP, Mahajan M, Nair VD, Gunasekaran G, Schwartz ME, Bardeesy N, Shalek AK, Rozenblatt-Rosen O, Regev A, Felli E, Pessaux P, Tanabe KK, Heikenwälder M, Schuster C, Pochet N, Zeisel MB, Fuchs BC, Hoshida Y, Baumert TF
Nat Commun. 2021 Sep 17;12(1):5525
Hepatitis B virus compartmentalization and single-cell differentiation in hepatocellular carcinoma.
Jühling F, Saviano A, Ponsolles C, Heydmann L, Crouchet E, Durand SC, El Saghire H, Felli E, Lindner V, Pessaux P, Pochet N, Schuster C, Verrier ER, Baumert TF
Life Sci Alliance. 2021 Sep;4(9):
Cell Culture Models for the Study of Hepatitis D Virus Entry and Infection.
Heuschkel MJ, Baumert TF, Verrier ER
Viruses. 2021 Aug 3;13(8):
[Jet virology: analysis of scientific publications during pandemics].
Verrier ER
Virologie (Montrouge). 2021 Jun 17;:
Hepatitis B virus-host interactions and novel targets for viral cure.
Ligat G, Verrier ER, Nassal M, Baumert TF
Curr Opin Virol. 2021 May 21;49:41-51
Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase (cGAS), a Multifaceted Platform of Intracellular DNA Sensing.
Verrier ER, Langevin C
Front Immunol. 2021 ;12:637399
Editorial: Nucleic Acid-Associated Inflammation.
Laguette N, Langevin C, Olagnier D, Torraca V, Vanpouille-Box C, Verrier ER
Front Immunol. 2021 ;12:791580
Liver Cirrhosis in Chronic Hepatitis B Patients Is Associated with Genetic Variations in DNA Repair Pathway Genes.
Rybicka M, Woziwodzka A, Sznarkowska A, Romanowski T, Stalke P, Dręczewski M, Verrier ER, Baumert TF, Bielawski KP
Cancers (Basel). 2020 Nov 7;12(11):
Targeting Viral cccDNA for Cure of Chronic Hepatitis B.
Ligat G, Goto K, Verrier E, Baumert TF
Curr Hepatol Rep. 2020 09;19(3):235-244
A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor.
Eller C, Heydmann L, Colpitts CC, El Saghire H, Piccioni F, Jühling F, Majzoub K, Pons C, Bach C, Lucifora J, Lupberger J, Nassal M, Cowley GS, Fujiwara N, Hsieh SY, Hoshida Y, Felli E, Pessaux P, Sureau C, Schuster C, Root DE, Verrier ER, Baumert TF
Nat Commun. 2020 Jun 1;11(1):2707
Genetic variation in IL-10 influences the progression of hepatitis B infection.
Rybicka M, Woziwodzka A, Sznarkowska A, Romanowski T, Stalke P, Dręczewski M, Verrier ER, Baumert TF, Bielawski KP
Int. J. Infect. Dis.. 2020 May 6;:
Targeting the Host for New Therapeutic Perspectives in Hepatitis D.
Turon-Lagot V, Saviano A, Schuster C, Baumert TF, Verrier ER
J Clin Med. 2020 Jan 14;9(1):
Hepatitis D Virus Infection Revisited.
Verrier ER, Majzoub K, Baumert TF
Gastroenterology. 2019 Oct 3;:
Hepatitis D virus: viral cycle and new therapeutic approaches.
Turon-Lagot V, Saviano A, Schuster C, Verrier ÉR
Virologie (Montrouge). 2019 06 1;23(3):149-159
Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of HCV-infected Cells and Liver to Identify Pathways Associated With Disease Development.
Lupberger J, Croonenborghs T, Roca Suarez AA, Van Renne N, Jühling F, Oudot MA, Virzì A, Bandiera S, Jamey C, Meszaros G, Brumaru D, Mukherji A, Durand SC, Heydmann L, Verrier ER, El Saghire H, Hamdane N, Bartenschlager R, Fereshetian S, Ramberger E, Sinha R, Nabian M, Everaert C, Jovanovic M, Mertins P, Carr SA, Chayama K, Dali-Youcef N, Ricci R, Bardeesy NM, Fujiwara N, Gevaert O, Zeisel MB, Hoshida Y, Pochet N, Baumert TF
Gastroenterology. 2019 Apr 9;:
Combined small molecule and loss-of-function screen uncovers estrogen receptor alpha and CAD as host factors for HDV infection and antiviral targets.
Verrier ER, Weiss A, Bach C, Heydmann L, Turon-Lagot V, Kopp A, El Saghire H, Crouchet E, Pessaux P, Garcia T, Pale P, Zeisel MB, Sureau C, Schuster C, Brino L, Baumert TF
Gut. 2019 Mar 4;:
The functional role of sodium taurocholate cotransporting polypeptide NTCP in the life cycle of hepatitis B, C and D viruses.
Eller C, Heydmann L, Colpitts CC, Verrier ER, Schuster C, Baumert TF
Cell. Mol. Life Sci.. 2018 Nov;75(21):3895-3905
Genetic and transcriptomic analyses provide new insights on the early antiviral response to VHSV in resistant and susceptible rainbow trout.
Verrier ER, Genet C, Laloë D, Jaffrezic F, Rau A, Esquerre D, Dechamp N, Ciobotaru C, Hervet C, Krieg F, Jouneau L, Klopp C, Quillet E, Boudinot P
BMC Genomics. 2018 Jun 19;19(1):482
Hepatitis B virus evasion from cGAS sensing in human hepatocytes.
Verrier ER, Yim SA, Heydmann L, El Saghire H, Bach C, Turon-Lagot V, Mailly L, Durand SC, Lucifora J, Durantel D, Pessaux P, Manel N, Hirsch I, Zeisel MB, Pochet N, Schuster C, Baumert TF
Hepatology. 2018 Apr 20;:
Solute carrier NTCP, a key actor in liver infections by hepatitis viruses and a promising antiviral target.
Verrier ER, Heydmann L, Baumert TF, Schuster C
Virologie (Montrouge). 2018 Feb 1;22(1):55-66
Extracellular lipid-free apolipoprotein E inhibits HCV replication and induces ABCG1-dependent cholesterol efflux.
Crouchet E, Lefèvre M, Verrier ER, Oudot MA, Baumert TF, Schuster C
Gut. 2017 05;66(5):896-907
Advancing hepatitis B virus entry inhibitors.
Verrier ER, Schuster C, Baumert TF
J. Hepatol.. 2017 04;66(4):677-679
Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes.
Verrier ER, Colpitts CC, Bach C, Heydmann L, Zona L, Xiao F, Thumann C, Crouchet E, Gaudin R, Sureau C, Cosset FL, McKeating JA, Pessaux P, Hoshida Y, Schuster C, Zeisel MB, Baumert TF
Cell Rep. 2016 Oct;17(5):1357-1368
Cell Culture Models for the Investigation of Hepatitis B and D Virus Infection.
Verrier ER, Colpitts CC, Schuster C, Zeisel MB, Baumert TF
Viruses. 2016 Sep 20;8(9):
Hepatitis B virus receptors and molecular drug targets.
Verrier ER, Colpitts CC, Sureau C, Baumert TF
Hepatol Int. 2016 Jul;10(4):567-73
Targeting Viral Entry for Treatment of Hepatitis B and C Virus Infections.
Colpitts CC, Verrier ER, Baumert TF
ACS Infect Dis. 2015 Sep 11;1(9):420-7
Retinoic acid-inducible gene 1 and sensing of hepatitis B virus revisited.
Verrier ER, Wieland S, Baumert TF
Hepatology. 2015 Sep;62(3):970-2
Host-targeting agents for treatment of hepatitis B virus infection.
Baumert TF, Verrier ER, Nassal M, Chung RT, Zeisel MB
Curr Opin Virol. 2015 Aug 8;14:41-46
A targeted functional RNAi screen uncovers Glypican 5 as an entry factor for hepatitis B and D viruses.
Verrier ER, Colpitts CC, Bach C, Heydmann L, Weiss A, Renaud M, Durand SC, Habersetzer F, Durantel D, Abou-Jaoude G, Lopez Ledesma MM, Felmlee DJ, Soumillon M, Croonenborghs T, Pochet N, Nassal M, Schuster C, Brino L, Sureau C, Zeisel MB, Baumert TF
Hepatology. 2015 Jul 29
Cyclic guanosine monophosphate/adenosine monophosphate synthase (cGAS), innate immune responses, and viral hepatitis.
Verrier ER, Gack MU, Baumert TF
Hepatology. 2014 Sep;60(3):1098-100