Dr MUELLER Christopher

Fiche personne

Coordonnées

IBMC
2 allée Konrad Roentgen
67084 STRASBOURG

03 88 41 70 27

Territoire

Alsace

Statut

Chercheur

Affiliation

IBMC - Institut de biologie moléculaire et cellulaire (IBMC)

Équipes/plateformes

Equipe CNRS UPR 3572 - Equipe "Immunologie, immunopathologie et chimie thérapeutique (I2CT) / Interactions physiopathologiques du système immunitaire avec son micro-environnement"

Publications

Epidermal maintenance of Langerhans cells relies on autophagy-regulated lipid metabolism.

Arbogast F, Sal-Carro R, Boufenghour W, Frenger Q, Bouis D, Filippi De La Palavesa L, Fauny JD, Griso O, Puccio H, Fima R, Huby T, Gautier EL, Molitor A, Carapito R, Bahram S, Romani N, Clausen BE, Voisin B, Mueller CG, Gros F, Flacher V

J Cell Biol. 2025 02 3;224(2):

Dysregulated myeloid differentiation in colitis is induced by inflammatory osteoclasts in a TNFα-dependent manner.

Madel MB, Ibáñez L, Ciucci T, Halper J, Boutin A, Beldi G, Lavanant AC, Garchon HJ, Rouleau M, Mueller CG, Peyrin-Biroulet L, Moulin D, Blin-Wakkach C, Wakkach A

Mucosal Immunol. 2024 09 25;:

Pseudomonas aeruginosa LecB suppresses immune responses by inhibiting transendothelial migration.

Sponsel J, Guo Y, Hamzam L, Lavanant AC, Pérez-Riverón A, Partiot E, Muller Q, Rottura J, Gaudin R, Hauck D, Titz A, Flacher V, Römer W, Mueller CG

EMBO Rep. 2023 03 1;:e55971

Lymphoid stromal cells - potential implications for the pathogenesis of CVID.

Cousin VN, Perez GF, Payne KJ, Voll RE, Rizzi M, Mueller CG, Warnatz K

Front Immunol. 2023 02 17;14:1122905

Engineering Novel 3D Models to Recreate High-Grade Osteosarcoma and its Immune and Extracellular Matrix Microenvironment.

Pierrevelcin M, Flacher V, Mueller CG, Vauchelles R, Guerin E, Lhermitte B, Pencreach E, Reisch A, Muller Q, Doumard L, Boufenghour W, Klymchenko AS, Foppolo S, Nazon C, Weingertner N, Martin S, Briandet C, Laithier V, Di Marco A, Bund L, Obrecht A, Villa P, Dontenwill M, Entz-Werlé N

Adv Healthc Mater. 2022 09 4;:e2200195

CD169 macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling.

Camara A, Lavanant AC, Abe J, Desforges HL, Alexandre YO, Girardi E, Igamberdieva Z, Asano K, Tanaka M, Hehlgans T, Pfeffer K, Pfeffer S, Mueller SN, Stein JV, Mueller CG

Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):

Chikungunya Virus Envelope Protein E2 Provides a Vector for Targeted Antigen Delivery to Human Dermal CD14 Dendritic Cells.

Brulefert A, Kraemer M, Cumin M, Selle A, Hoste A, Gad HH, Rühl J, Madinier JB, Chaloin O, Münz C, Desprès P, Mueller CG, Flacher V

J Invest Dermatol. 2021 12;141(12):2985-2989.e5

Vitamin D3-elicited CD14+ human skin dendritic cells promote thymic stromal lymphopoietin-independent type 2 T-helper responses.

Brulefert A, Hoste A, Muller Q, Fauny JD, Mueller CG, Flacher V

Allergy. 2021 07;76(7):2044-2056

Current Clinical and Pre-Clinical Imaging Approaches to Study the Cancer-Associated Immune System.

Mueller CG, Gaiddon C, Venkatasamy A

Front Immunol. 2021 ;12:716860

[The sinusoidal microenvironment regulates the niche and the differentiation of lymph node macrophages].

Mueller CG, Camara A, Flacher V

Med Sci (Paris). 2020 Oct;36(10):835-838

Tenascin-C orchestrates an immune suppressive tumor microenvironment in oral squamous cell carcinoma.

Spenlé C, Loustau T, Murdamoothoo D, Erne W, Beghelli-de la Forest Divonne S, Veber R, Petti L, Bourdely P, Mörgelin M, Brauchle EM, Crémel G, Randrianarisoa V, Camara A, Rekima S, Schaub S, Nouhen K, Imhof T, Hansen U, Paul N, Carapito R, Pythoud N, Hirschler A, Carapito C, Dumortier H, Mueller CG, Koch M, Schenke-Layland K, Kon S, Sudaka A, Anjuere F, Van Obberghen-Schilling E, Orend G

Cancer Immunol Res. 2020 Jul 14;:

Genetically-achieved disturbances to the expression levels of TNFSF11 receptors modulate the effects of zoledronic acid on growing mouse skeletons.

Vargas-Franco JW, Castaneda B, Gama A, Mueller CG, Heymann D, Rédini F, Lézot F

Biochem Pharmacol. 2019 10;168:133-148

Of skin and bone: did Langerhans cells and osteoclasts evolve from a common ancestor?

Mueller CG, Voisin B

J Anat. 2019 08;235(2):412-417

Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche.

Camara A, Cordeiro OG, Alloush F, Sponsel J, Chypre M, Onder L, Asano K, Tanaka M, Yagita H, Ludewig B, Flacher V, Mueller CG

Immunity. 2019 06 18;50(6):1467-1481.e6

sp-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo.

Schaeffer E, Sánchez-Fernández EM, Gonçalves-Pereira R, Flacher V, Lamon D, Duval M, Fauny JD, García Fernández JM, Mueller CG, Ortiz Mellet C

Eur J Med Chem. 2019 May 1;169:111-120

Mannoside Glycolipid Conjugates Display Antiviral Activity Against Ebola Virus.

Reynard O, Schaeffer E, Volchkova VA, Cimarelli A, Mueller CG, Volchkov VE

J Infect Dis. 2018 11 22;218(suppl_5):S666-S671

Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups.

Navet B, Vargas-Franco JW, Gama A, Amiaud J, Choi Y, Yagita H, Mueller CG, Rédini F, Heymann D, Castaneda B, Lézot F

J Clin Med. 2018 Nov 8;7(11):

The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases.

Navet B, Ando K, Vargas-Franco JW, Brion R, Amiaud J, Mori K, Yagita H, Mueller CG, Verrecchia F, Dumars C, Heymann MF, Heymann D, Lézot F

Cancers (Basel). 2018 Oct 24;10(11):

Inhibition of dengue virus infection by mannoside glycolipid conjugates.

Schaeffer E, Flacher V, Neuberg P, Hoste A, Brulefert A, Fauny JD, Wagner A, Mueller CG

Antiviral Res.. 2018 Apr 6;154:116-123

Cellular and Vascular Components of Tertiary Lymphoid Structures.

Mueller CG, Nayar S, Gardner D, Barone F

Methods Mol Biol. 2018 ;1845:17-30

Porphyrin Derivatives Inhibit the Interaction between Receptor Activator of NF-κB and Its Ligand.

Chypre M, Madel MB, Chaloin O, Blin-Wakkach C, Morice C, Mueller CG

ChemMedChem. 2017 10 20;12(20):1697-1702

Therapeutical modulation of plasmacytoid dendritic cells in experimental arthritis.

Nehmar R, Alsaleh G, Voisin B, Flacher V, Mariotte A, Saferding V, Puchner A, Niederreiter B, Vandamme T, Schabbauer G, Kastner P, Chan S, Kirstetter P, Holcmann M, Mueller C, Sibilia J, Bahram S, Blüml S, Georgel P

. 2017 Aug;:

Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis.

Onder L, Mörbe U, Pikor N, Novkovic M, Cheng HW, Hehlgans T, Pfeffer K, Becher B, Waisman A, Rülicke T, Gommerman J, Mueller CG, Sawa S, Scandella E, Ludewig B

Immunity. 2017 07 18;47(1):80-92.e4

RANK/RANKL/OPG Signalization Implication in Periodontitis: New Evidence from a RANK Transgenic Mouse Model.

Sojod B, Chateau D, Mueller CG, Babajko S, Berdal A, Lézot F, Castaneda B

Front Physiol. 2017 ;8:338

Interleukin-36 potently stimulates human M2 macrophages, Langerhans cells and keratinocytes to produce pro-inflammatory cytokines.

Dietrich D, Martin P, Flacher V, Sun Y, Jarrossay D, Brembilla N, Mueller C, Arnett HA, Palmer G, Towne J, Gabay C

Cytokine. 2016 08;84:88-98

Characterization and application of two RANK-specific antibodies with different biological activities.

Chypre M, Seaman J, Cordeiro OG, Willen L, Knoop KA, Buchanan A, Sainson RC, Williams IR, Yagita H, Schneider P, Mueller CG

Immunol Lett. 2016 Mar;171:5-14

Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL.

Cordeiro OG, Chypre M, Brouard N, Rauber S, Alloush F, Romera-Hernandez M, Bénézech C, Li Z, Eckly A, Coles MC, Rot A, Yagita H, Léon C, Ludewig B, Cupedo T, Lanza F, Mueller CG

PLoS One. 2016 ;11(3):e0151848