Pr DEBELLE Laurent

Fiche personne

Coordonnées

UMR CNRS 7369 MEDyC
Campus Moulin de la Housse
BP 1039
51687 Reims Cedex 2

03 26 91 34 35

laurent.debelle@univ-reims.fr

Territoire

Champagne-Ardenne

Statut

Enseignant-Chercheur

Affiliation

Université de Reims Champagne-Ardenne (URCA)

UMR CNRS 7369 MEDyC - Matrice Extracellulaire et Dynamique Cellulaire MEDyC (MEDyC)

Équipes/plateformes

UMR 7369 MEDyC - Equipe "Modélisation et Imagerie Multi-Echelles"

Publications

Exploring aortic stiffness in aging mice: a comprehensive methodological overview.

Vanalderwiert L, Henry A, de Souza E Silva JM, Carvajal-Berrio D, Debelle L, Wahart A, Marzi J, Schenke-Layland K, Faury G, Six I, Schmelzer CEH, Brinckmann J, Steenbock H, Almagro S, Delacoux F, Jaisson S, Gillery P, Maurice P, Sartelet H, Bennasroune A, Duca L, Romier B, Blaise S

Aging (Albany NY). 2024 12 2;null:

METABOLIC SYNDROME-ASSOCIATED MURINE AORTIC WALL STIFFENING IS ASSOCIATED WITH PREMATURE ELASTIC FIBERS AGING.

Vanalderwiert L, Henry A, Wahart A, Carvajal Berrio DA, Brauchle EM, El Kaakour L, Schenke-Layland K, Brinckmann J, Steenbock H, Debelle L, Six I, Faury G, Jaisson S, Gillery P, Durlach V, Sartelet H, Maurice P, Bennasroune A, Martiny L, Duca L, Romier B, Blaise S

Am J Physiol Cell Physiol. 2024 07 1;:

Structural and physical basis for the elasticity of elastin.

Depenveiller C, Baud S, Belloy N, Bochicchio B, Dandurand J, Dauchez M, Pepe A, Pomès R, Samouillan V, Debelle L

Q Rev Biophys. 2024 03 19;:1-78

Prediction, screening and characterization of novel bioactive tetra-peptide matrikines for skin rejuvenation.

Jariwala N, Ozols M, Eckersley A, Mambwe B, Watson REB, Zeef L, Gilmore A, Debelle L, Bell M, Bradley EJ, Doush Y, Keenan A, Courage C, Leroux R, Peschard O, Mondon P, Ringenbach C, Bernard L, Pitois A, Sherratt MJ

Br J Dermatol. 2024 02 20;:

Challenging Level Of Rigid-body Approach Involving Numerical Elements (CHLORAINE) applied to repeated elastin peptides.

Depenveiller C, Wong H, Crowet JM, Debelle L, Baud S, Dauchez M, Belloy N

J Struct Biol. 2023 06 19;:107986

Matrikines as Mediators of Tissue Remodelling.

Jariwala N, Ozols M, Bell M, Bradley E, Gilmore A, Debelle L, Sherratt MJ

Adv Drug Deliv Rev. 2022 Apr 1;:114240

Early Alterations of Intra-Mural Elastic Lamellae Revealed by Synchrotron X-ray Micro-CT Exploration of Diabetic Aortas.

Ben Zemzem A, Liang X, Vanalderwiert L, Bour C, Romier-Crouzet B, Blaise S, Sherratt MJ, Weitkamp T, Dauchez M, Baud S, Passat N, Debelle L, Almagro S

Int J Mol Sci. 2022 Mar 17;23(6):

Investigation of antiparasitic activity of ten European tree bark extracts on and bioguided identification of triterpenes in barks.

Darme P, Spalenka J, Hubert J, Escotte-Binet S, Debelle L, Villena I, Sayagh C, Borie N, Martinez A, Bertaux B, Voutquenne-Nazabadioko L, Renault JH, Aubert D

Antimicrob Agents Chemother. 2021 Oct 11;:AAC0109821

X-ray microtomography reveals a lattice-like network within aortic elastic lamellae.

Ben Zemzem A, Genevaux A, Wahart A, Bodey AJ, Blaise S, Romier-Crouzet B, Jonquet J, Bour C, Cogranne R, Beauseroy P, Dauchez M, Sherratt MJ, Debelle L, Almagro S

FASEB J. 2021 Oct;35(10):e21844

Structural Analysis of Nonapeptides Derived from Elastin.

Hernández B, Crowet JM, Thiery J, Kruglik SG, Belloy N, Baud S, Dauchez M, Debelle L

Biophys. J.. 2020 Apr 25;:

Elastin molecular aging promotes MDA-MB-231 breast cancer cell invasiveness.

Salesse S, Odoul L, Chazée L, Garbar C, Duca L, Martiny L, Mahmoudi R, Debelle L

FEBS Open Bio. 2018 Sep;8(9):1395-1404

Production of Elastin-Derived Peptides Contribute to the Development of Non-Alcoholic Steatohepatitis.

Romier B, Ivaldi C, Sartelet H, Heinz A, Schmelzer CEH, Garnotel R, Guillot A, Jonquet J, Bertin E, Guéant JL, Alberto JM, Bronowicki JP, Amoyel J, Hocine T, Duca L, Maurice P, Bennasroune A, Martiny L, Debelle L, Durlach V, Blaise S

Diabetes. 2018 May 25;:

New Insights into Molecular Organization of Human Neuraminidase-1: Transmembrane Topology and Dimerization Ability.

Maurice P, Baud S, Bocharova OV, Bocharov EV, Kuznetsov AS, Kawecki C, Bocquet O, Romier B, Gorisse L, Ghirardi M, Duca L, Blaise S, Martiny L, Dauchez M, Efremov RG, Debelle L

Sci Rep. 2016 Dec;6:38363

Impact of sialic acids on the molecular dynamic of bi-antennary and tri-antennary glycans.

Guillot A, Dauchez M, Belloy N, Jonquet J, Duca L, Romier B, Maurice P, Debelle L, Martiny L, Durlach V, Baud S, Blaise S

Sci Rep. 2016 Oct;6:35666

Pregnancy outcome following frozen embryo transfer after artificial cycle or treatment by clomiphene citrate.

Jouan C, Emonard V, Ruggeri P, Debelle L, Hincourt N, Lorquet S, Dechenne V, Giner C, Dubois M, Perrier d'Hauterive S, Nisolle M

Gynecol. Endocrinol.. 2016 Oct;32(10):807-810

Matrix ageing and vascular impacts: focus on elastin fragmentation.

Duca L, Blaise S, Romier B, Laffargue M, Gayral S, El Btaouri H, Kawecki C, Guillot A, Martiny L, Debelle L, Maurice P

Cardiovasc. Res.. 2016 06;110(3):298-308

Protein carbamylation is a hallmark of aging.

Gorisse L, Pietrement C, Vuiblet V, Schmelzer CE, Köhler M, Duca L, Debelle L, Fornès P, Jaisson S, Gillery P

Proc. Natl. Acad. Sci. U.S.A.. 2016 Feb;113(5):1191-6

The Elastin Receptor Complex: A Unique Matricellular Receptor with High Anti-tumoral Potential.

Scandolera A, Odoul L, Salesse S, Guillot A, Blaise S, Kawecki C, Maurice P, El Btaouri H, Romier-Crouzet B, Martiny L, Debelle L, Duca L

Front Pharmacol. 2016 ;7:32

Autophagy is decreased in triple-negative breast carcinoma involving likely the MUC1-EGFR-NEU1 signalling pathway.

Garbar C, Mascaux C, Giustiniani J, Salesse S, Debelle L, Antonicelli F, Merrouche Y, Bensussan A

Int J Clin Exp Pathol. 2015 May 1;8(5):4344-55. eCollection 2015.

Uncoupling of Elastin Complex Receptor during In Vitro Aging Is Related to Modifications in Its Intrinsic Sialidase Activity and the Subsequent Lactosylceramide Production.

Scandolera A, Rabenoelina F, Chaintreuil C, Rusciani A, Maurice P, Blaise S, Romier-Crouzet B, El Btaouri H, Martiny L, Debelle L, Duca L

PLoS One. 2015 Jun 18;10(6):e0129994

Elastin-derived peptides are new regulators of thrombosis.

Kawecki C, Hezard N, Bocquet O, Poitevin G, Rabenoelina F, Kauskot A, Duca L, Blaise S, Romier B, Martiny L, Nguyen P, Debelle L, Maurice P

Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2570-8

Elastin-derived peptides potentiate atherosclerosis through the immune Neu1-PI3Kgamma pathway.

Gayral S, Garnotel R, Castaing-Berthou A, Blaise S, Fougerat A, Berge E, Montheil A, Malet N, Wymann MP, Maurice P, Debelle L, Martiny L, Martinez LO, Pshezhetsky AV, Duca L, Laffargue M

Cardiovasc Res. 2014 Apr 1;102(1):118-27

Elastin-derived peptides are new regulators of insulin resistance development in mice.

Blaise S, Romier B, Kawecki C, Ghirardi M, Rabenoelina F, Baud S, Duca L, Maurice P, Heinz A, Schmelzer CE, Tarpin M, Martiny L, Garbar C, Dauchez M, Debelle L, Durlach V

Diabetes. 2013 Nov;62(11):3807-16

Elastin peptides in aging and pathological conditions.

Baud S, Duca L, Bochicchio B, Brassart B, Belloy N, Pepe A, Dauchez M, Martiny L, Debelle L

Biomol Concepts. 2013 Feb;4(1):65-76

Interaction between the elastin peptide VGVAPG and human elastin binding protein.

Blanchevoye C, Floquet N, Scandolera A, Baud S, Maurice P, Bocquet O, Blaise S, Ghoneim C, Cantarelli B, Delacoux F, Dauchez M, Efremov RG, Martiny L, Duca L, Debelle L

J Biol Chem. 2013 Jan 11;288(2):1317-28