Pr DELAGE-MOURROUX Régis

Fiche personne

Coordonnées

UFR Sciences et Techniques
Université de Franche-Comté
16 route de Gray

25030 BESANCON

03 81 66 65 44

Territoire

Franche-Comté

Statut

Enseignant-Chercheur

Affiliation

Inserm UMR 1098 "Interaction Hôte-Greffon-Tumeur, Ingénierie Cellulaire et Génique" (Inserm UMR1098 RIGHT)

Université de Franche-Comté (UFC)

Équipes/plateformes

Equipe UMR 1098 - Equipe "Thérapeutique Immuno-Moléculaire des Cancers (TIM-C) - Autophagy, epigenetics and T-cell Immunity in cancer (AETIC)"

Recherche

Expertises :
- Recherche:Biologie Cellulaire
- Recherche:Biologie Moléculaire
- Cancer:Cerveau

Publications

The ATG8 Family Proteins GABARAP and GABARAPL1 Target Antigen to Dendritic Cells to Prime CD4 and CD8 T Cells.

Fonderflick L, Baudu T, Adotévi O, Guittaut M, Adami P, Delage-Mourroux R

Cells. 2022 09 6;11(18):

EZH2 and KDM6B Expressions Are Associated with Specific Epigenetic Signatures during EMT in Non Small Cell Lung Carcinomas.

Lachat C, Bruyère D, Etcheverry A, Aubry M, Mosser J, Warda W, Herfs M, Hendrick E, Ferrand C, Borg C, Delage-Mourroux R, Feugeas JP, Guittaut M, Hervouet E, Peixoto P

Cancers (Basel). 2020 Dec 5;12(12):

EMT is associated with an epigenetic signature of ECM remodeling genes.

Peixoto P, Etcheverry A, Aubry M, Missey A, Lachat C, Perrard J, Hendrick E, Delage-Mourroux R, Mosser J, Borg C, Feugeas JP, Herfs M, Boyer-Guittaut M, Hervouet E

Cell Death Dis. 2019 Feb 27;10(3):205

Is Overexpressed in Triple Negative Breast Cancer and Its In Vitro Extinction Leads to the Inhibition of Pro-Cancer Phenotypes.

Claude-Taupin A, Fonderflick L, Gauthier T, Mansi L, Pallandre JR, Borg C, Perez V, Monnien F, Algros MP, Vigneron M, Adami P, Delage-Mourroux R, Peixoto P, Herfs M, Boyer-Guittaut M, Hervouet E

Cells. 2018 Dec 6;7(12):

Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma.

Hervouet E, Peixoto P, Delage-Mourroux R, Boyer-Guittaut M, Cartron PF

Clin Epigenetics. 2018 ;10:17

GABARAPL1 tumor suppressive function is independent of its conjugation to autophagosomes in MCF-7 breast cancer cells.

Poillet-Perez L, Jacquet M, Hervouet E, Gauthier T, Fraichard A, Borg C, Pallandre JR, Gonzalez BJ, Ramdani Y, Boyer-Guittaut M, Delage-Mourroux R, Despouy G

Oncotarget. 2017 Aug;8(34):55998-56020

Carbon nanotubes as gene carriers: Focus on internalization pathways related to functionalization and properties.

Caoduro C, Hervouet E, Girard-Thernier C, Gharbi T, Boulahdour H, Delage-Mourroux R, Pudlo M

Acta Biomater. 2017 Feb;49:36-44

Nanovectorization of DNA Through Cells Using Protamine Complexation.

Boukari K, Caoduro C, Kacem R, Skandrani N, Borg C, Boulahdour H, Gharbi T, Delage-Mourroux R, Hervouet E, Pudlo M, Picaud F

J. Membr. Biol.. 2016 Aug;249(4):493-501

Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7beta-hydroxycholesterol-, and 24(S)-hydroxycholesterol: Protective effects of alpha-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3).

Nury T, Zarrouk A, Mackrill JJ, Samadi M, Durand P, Riedinger JM, Doria M, Vejux A, Limagne E, Delmas D, Prost M, Moreau T, Hammami M, Delage-Mourroux R, O'Brien NM, Lizard G

Steroids. 2015 Feb 12. pii: S0039-128X(15)00059-8

Proximity Ligation In situ Assay is a Powerful Tool to Monitor Specific ATG Protein Interactions following Autophagy Induction.

Gauthier T, Claude-Taupin A, Delage-Mourroux R, Boyer-Guittaut M, Hervouet E

PLoS ONE. 2015 ;10(6):e0128701

The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models.

Hervouet E, Claude-Taupin A, Gauthier T, Perez V, Fraichard A, Adami P, Despouy G, Monnien F, Algros MP, Jouvenot M, Delage-Mourroux R, Boyer-Guittaut M

BMC Cancer. 2015 Oct 17;15:729

Use of epigenetic modulators as a powerful adjuvant for breast cancer therapies.

Claude-Taupin A, Boyer-Guittaut M, Delage-Mourroux R, Hervouet E

Methods Mol Biol. 2015;1238:487-509

Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy.

Poillet-Perez L, Despouy G, Delage-Mourroux R, Boyer-Guittaut M

Redox Biol. 2014 Dec 10;4C:184-192

The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells.

Boyer-Guittaut M, Poillet L, Liang Q, Bole-Richard E, Ouyang X, Benavides GA, Chakrama FZ, Fraichard A, Darley-Usmar VM, Despouy G, Jouvenot M, Delage-Mourroux R, Zhang J

Autophagy. 2014 Jun;10(6):986-1003

Induction of oxiapoptophagy, a mixed mode of cell death associated with oxidative stress, apoptosis and autophagy, on 7-ketocholesterol-treated 158N murine oligodendrocytes: impairment by alpha-tocopherol.

Nury T, Zarrouk A, Vejux A, Doria M, Riedinger JM, Delage-Mourroux R, Lizard G

Biochem Biophys Res Commun. 2014 Apr 11;446(3):714-9

QSOX1 inhibits autophagic flux in breast cancer cells.

Poillet L, Pernodet N, Boyer-Guittaut M, Adami P, Borg C, Jouvenot M, Delage-Mourroux R, Despouy G

PLoS One. 2014 Jan 24;9(1):e86641

Epigenetic regulation of estrogen signaling in breast cancer.

Hervouet E, Cartron PF, Jouvenot M, Delage-Mourroux R

Epigenetics. 2013 Mar;8(3):237-45

Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein.

Seguin-Py S, Lucchi G, Croizier S, Chakrama FZ, Despouy G, Le Grand JN, Ducoroy P, Boireau W, Boyer-Guittaut M, Jouvenot M, Fraichard A, Delage-Mourroux R

Biochimie. 2012 Mar;94(3):748-58