Fiche publication


Date publication

février 2015

Auteurs

Membres identifiés du Cancéropôle Est :
Dr FRISCH Benoit , Dr LAVALLE Philippe , Pr SCHAAF Pierre


Tous les auteurs :
Rios C, Longo J, Zahouani S, Garnier T, Vogt C, Reisch A, Senger B, Boulmedais F, Hemmerle J, Benmlih K, Frisch B, Schaaf P, Jierry L, Lavalle P

Résumé

Using modified beta-galactosidase covalently linked to cross-linked polyelectrolyte multilayers (PEM), catalytically active materials have been designed. Their enzymatic activity can be modulated, partially in a reversible way, simply by stretching. This strategy, based on enzyme conformational changes, constitutes a new tool for the development of biocatalytic mechano-responsive materials.

Référence

Chem Commun (Camb). 2015 Feb 26.