Fiche publication
Date publication
février 2015
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BOREL Christian
,
Pr VELTEN Michel
,
Dr WORONOFF Anne-Sophie
Tous les auteurs :
Jegu J, Belot A, Borel C, Daubisse-Marliac L, Tretarre B, Ganry O, Guizard AV, Bara S, Troussard X, Bouvier V, Woronoff AS, Colonna M, Velten M
Lien Pubmed
Résumé
OBJECTIVE: To provide head and neck squamous cell carcinoma (HNSCC) survival estimates with respect to patient previous history of cancer. MATERIALS AND METHODS: Data from ten French population-based cancer registries were used to establish a cohort of all male patients presenting with a HNSCC diagnosed between 1989 and 2004. Vital status was updated until December 31, 2007. The 5-year overall and net survival estimates were assessed using the Kaplan-Meier and Pohar-Perme estimators, respectively. Multivariate Cox regression models were used to assess the effect of cancer history adjusted for age and year of HNSCC diagnosis. RESULTS: Among the cases of HNSCC, 5553 were localized in the oral cavity, 3646 in the oropharynx, 3793 in the hypopharynx and 4550 in the larynx. From 11.0% to 16.8% of patients presented with a previous history of cancer according to HNSCC. Overall and net survival were closely tied to the presence, or not, of a previous cancer. For example, for carcinoma of the oral cavity, the five-year overall survival was 14.0%, 5.9% and 36.7% in case of previous lung cancer, oesophagus cancer or no cancer history, respectively. Multivariate analyses showed that previous history of cancer was a prognosis factor independent of age and year of diagnosis (p
Référence
Oral Oncol. 2015 Feb 13. pii: S1368-8375(15)00022-6
