Fiche publication
Date publication
janvier 2009
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GUIHARD Sébastien
,
Pr NOEL Georges
Tous les auteurs :
Guihard S, Noel G
Lien Pubmed
Résumé
Merkel cell carcinoma (MCC) is a rare neuroendocrine carcinoma of the skin with features of epithelial differentiation. It occurs in older patients, appears on sun exposed areas and its incidence is increasing. The surgical excision with negative margins is the first treatment and adjuvant local irradiation now is well established but regional adjuvant (lymph nodes dissection or radiation therapy) remains discussed. MCC is chemosensitive but rarely chemocurable in patients with metastasis or locally advanced tumors. The most used therapy is platinum-based polychemotherapy.
Référence
Cancer Radiother. 2009 Jan;13(1):47-54
