[Acute interstitial nephritis of fluindione: about three cases]

Date publication

octobre 2008

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MARTIN Laurent

Tous les auteurs :
Beauchamp C, Enache I, Haskour A, Martin L

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/18417438

Résumé

Acute interstitial nephritis is a frequent cause of acute renal failure, representing about 10% of all biopsied cases. Early recognition of drug-induced acute immunoallergic interstitial nephritis prevents the development of severe chronic renal injury. The list of imputable drugs includes phenindione, a vitamin K antagonist. Fluindione which is also an indanedione derivative is another vitamin K antagonist. We report three biopsy-proved cases of fluindione related acute interstitial nephritis with recovery of renal function after drug withdrawal and prednisone therapy.

Référence

Nephrol Ther. 2008 Oct;4(5):339-46