ETV6/GOT1 fusion in a case of t(10;12)(q24;p13)-positive myelodysplastic syndrome.

Date publication

mars 2008

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MAUVIEUX Laurent

Tous les auteurs :
Struski S, Mauvieux L, Gervais C, Helias C, Liu KL, Lessard M

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/18310541

Résumé

The ETV6/GOT1 fusion, resulting from t(10;12) (q24;p13), has been recently described in a myelodysplastic syndrome. We reported a second case of t(10;12)-positive myelodysplastic syndrome in whom fluorescent in situ hybridization confirmed the non-random translocation but molecular biology analyses revealed a ETV6/GOT1 chimera varying from the first case described.

Référence

Haematologica. 2008 Mar;93(3):467-8.