Fiche publication
Date publication
janvier 2008
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GAIDDON Christian
,
Dr LOEFFLER Jean-Philippe
Tous les auteurs :
Leyva L, Malek F, Benzina S, Denis JM, Gueulette J, Dufour P, Gaiddon C, Loeffler JP, Sirlin C, Pfeffer M, Bischoff P
Résumé
The effect of combining RDC-11 (a new ruthenium organometallic complex) and fast neutrons (high-LET radiations) has been evaluated in RDM4 and U-87 tumor cell lines. After co-treatment, a substantial reduction of cell growth was recorded, which appears not to be correlated with the induction of apoptosis.
Référence
Lett Drug Des Discov. 2008 Jan;5(1):1-6
