Fiche publication
Date publication
mars 2007
Auteurs
Membres identifiés du Cancéropôle Est :
Dr NUZILLARD Jean-Marc
Tous les auteurs :
Nuzillard JM, Haudrechy A
Résumé
The QUIRAL computer program analyzes the 3D structure of a target organic molecule to find which sugar(s) can be used as a starting material for its synthesis. The program also proposes schemes for the preparation of rare or unavailable sugars whose chiral centers fit with those of the target molecule. Castanospermine, an anti-HIV natural compound is chosen as an example to illustrate what the QUIRAL program achieves. (c) 2007 Elsevier Ltd. All rights reserved.
Référence
Tetrahedron Lett. 2007 Mar 26;48(13):2311-3.
