Contribution of Raman spectroscopy in nephrology: a candidate technique to detect hydroxyethyl starch of third generation in osmotic renal lesions.

Date publication

octobre 2015

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PIOT Olivier

Tous les auteurs :
Vuiblet V, Nguyen TT, Wynckel A, Fere M, Van-Gulick L, Untereiner V, Birembaut P, Rieu P, Piot O

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/26413856

Résumé

BACKGROUND AND OBJECTIVES: HydroxyEthyl Starch (HES) has been one of the most commonly used colloid volume expanders in intensive care units for over 50 years. The first and second generation HES, with a high molecular weight (>/=200 kD) and a high degree of substitution (>/=0.5), has been associated with both renal dysfunction and osmotic nephrosis-like lesions in histological studies. Recently, third generation HES (130 kD/

Référence

Analyst. 2015 Oct 12;140(21):7382-90