Protocol Design Challenges in the Detection of Awareness in Aware Subjects Using EEG Signals.

Date publication

décembre 2014

Auteurs

Membres identifiés du Cancéropôle Est :
Pr AUBRY Régis , Dr PAZART Lionel , Pr MOULIN Thierry , Mme HENRIQUES Julie

Tous les auteurs :
Henriques J, Gabriel D, Grigoryeva L, Haffen E, Moulin T, Aubry R, Pazart L, Ortega JP

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/25488924

Résumé

Recent studies have evidenced serious difficulties in detecting covert awareness with electroencephalography-based techniques both in unresponsive patients and in healthy control subjects. This work reproduces the protocol design in two recent mental imagery studies with a larger group comprising 20 healthy volunteers. The main goal is assessing if modifications in the signal extraction techniques, training-testing/cross-validation routines, and hypotheses evoked in the statistical analysis, can provide solutions to the serious difficulties documented in the literature. The lack of robustness in the results advises for further search of alternative protocols more suitable for machine learning classification and of better performing signal treatment techniques. Specific recommendations are made using the findings in this work.

Référence

Clin EEG Neurosci. 2014 Dec 8. pii: 1550059414560397.