Fiche publication
Date publication
mai 2006
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BELLEMIN-LAPONNAZ Stéphane
Tous les auteurs :
Poyatos M, Maisse-Francois A, Bellemin-Laponnaz S, Gade LH
Résumé
Reaction of 1-mesitylimidazole with 2-chlorobenzoxazole gave the 2-benzoxazolyl imidazolium salt bzoxcarbH(+)Cl- (1), which was converted to the silver N-heterocyclic carbene complex [Ag-1(bzoxcarb)Cl] (2) by reaction with Ag2O in dichloromethane. The crystal structure analysis confirmed the monomeric nature of complex 2. The silver complex 2 was reacted with [PdCl2(COD)] to yield the corresponding palladium complex [PdCl2(bzoxcarb)] (3), for which an X-ray diffraction study established a distorted square planar configuration with the imidazolyl and the oxazolyl ring lying within the molecular plane. Upon direct reaction of the imidazoliurn salt 1 with Pd(OAc)(2)/NaI, a bis-carbene palladium complex [PdI2(bzoxcarb)(2)] (4) was obtained. The rhodiumcomplex [RhCl(bzoxcarb)(CO)] (5) was prepared in high yield in a one-step reaction of 1 with [Rh(acac)(CO)(2)] (acac = acetylacetonate). The silver N-heterocyclic carbene complex 2 was also used as carbene transfer reagent in the synthesis of the platinum complex [PtCl2(bzoxcarb)] (6), which was found to be an active catalyst for the hydrosilylation of alkenes and atkynes.
Référence
. 2006 May 8;25(10):2634-41.
