Remission with ursodeoxycholic acid of type 1 autoimmune hepatitis resistant to azathioprine and steroids.

Date publication

novembre 2005

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DI MARTINO Vincent

Tous les auteurs :
Duclos-Vallee JC, Di Martino V, Cazier A, Ballot E, Johanet C, Yamamoto AM, Emile JF, Guettier C, Coutarel P, Cadranel JF

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/16505766

Résumé

Combination therapy with steroids and azathioprine is the reference treatment for autoimmune hepatitis, but potential adverse effects are numerous and intolerance can occur. We report a patient with a well-documented type 1 autoimmune hepatitis intolerant to corticosteroids and azathioprine therapy, in whom eight years of ursodeoxycholic acid monotherapy was associated with biochemical and histological remission.

Référence

Gastroenterol Clin Biol. 2005 Nov;29(11):1173-6.