Fiche publication
Date publication
novembre 2004
Auteurs
Membres identifiés du Cancéropôle Est :
Dr FREUND Jean-Noël
Tous les auteurs :
Wang L, Klopot A, Freund JN, Dowling LN, Krasinski SD, Fleet JC
Lien Pubmed
Résumé
Calbindin D9k (CaBP) is critical for intestinal calcium absorption; its in vivo expression is restricted to differentiated enterocytes of the small intestine. Our goal was to identify factors controlling the transcriptional regulation of this gene in the human intestine. Both the natural gene and a 4600-bp promoter construct were strongly regulated by differentiation (>100-fold) but not by treatment with 1,25(OH)2 vitamin D (
Référence
Am J Physiol Gastrointest Liver Physiol. 2004 Nov;287(5):G943-53
