Fiche publication
Date publication
juillet 2004
Auteurs
Membres identifiés du Cancéropôle Est :
Dr WASYLYK Bohdan
Tous les auteurs :
Lemaire F, Millon R, Muller D, Rabouel Y, Bracco L, Abecassis J, Wasylyk B
Lien Pubmed
Résumé
We report that homeodomain-only protein (HOP) is expressed in the suprabasal layer of normal upper aerodigestive tract epithelium and expression strongly decreases in hypopharyngeal carcinoma. Interestingly, HOP has very recently been shown to be a tumour suppressor involved in differentiation, suggesting that HOP may have a similar role in head and neck squamous cell carcinoma (HNSSC).
Référence
Br J Cancer. 2004 Jul 19;91(2):258-61.
