Fiche publication
Date publication
octobre 2014
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MATHELIN Carole
Tous les auteurs :
Gassmann AS, Gonzalez M, Mathelin C
Lien Pubmed
Résumé
OBJECTIVE: The aim of this revue was to estimate the level of breast cancer risk among female flight attendants. MATERIAL AND METHODS: The selected articles were taken from the PUBMED database, between January 1st 1995 and December 31st 2013 by the means of the following keywords: "breast cancer", "flight attendants", "airline cabin crew" and "flight personnel". Seventeen articles were finally selected. RESULTS: The incidence of breast cancer is significantly higher among female flights attendants [standardized incidence ratio (SIR) 1.04-5.24, 95% CI 1.00-17.38]. However, no studies have demonstrated a significant increase of mortality by breast cancer [standardized mortality ratio (SMR) 1.0-1.28, 95% CI 0.54-3.7]. The circadian rhythm disruption through night work and time zones leading to disorder of melatonin secretion just as exposure to cosmic radiation could account for this increase of risk. DISCUSSION AND CONCLUSION: A medical supervision concerning breast cancer for flight attendants is recommended. Additional studies seem to be necessary in order to estimate the additional role of other risk factors, in particular hormonal factor.
Référence
Gynecol Obstet Fertil. 2014 Oct 31. pii: S1297-9589(14)00276-8
