Fiche publication


Date publication

septembre 2016

Journal

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GHIRINGHELLI François , Dr LADOIRE Sylvain , Pr COTTIN Yves , Pr VERGELY Catherine


Tous les auteurs :
Guenancia C, Lefebvre A, Cardinale D, Yu AF, Ladoire S, Ghiringhelli F, Zeller M, Rochette L, Cottin Y, Vergely C

Résumé

Patients with metabolic syndrome have a greater risk of cardiovascular disease, although their susceptibility to chemotherapy-induced cardiac disease is not well documented. The aim of this meta-analysis was to assess associations between obesity or being overweight and cardiotoxicity from anthracyclines and sequential anthracyclines and trastuzumab in patients with breast cancer.

Mots clés

Anthracyclines, adverse effects, Antibiotics, Antineoplastic, adverse effects, Antineoplastic Combined Chemotherapy Protocols, adverse effects, Body Mass Index, Breast Neoplasms, complications, Cardiotoxicity, Female, Heart Diseases, chemically induced, Humans, Obesity, complications, Odds Ratio, Risk Assessment, Risk Factors, Trastuzumab, adverse effects

Référence

J. Clin. Oncol.. 2016 Sep;34(26):3157-65