Fiche publication
Date publication
janvier 2017
Journal
British journal of cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CLAVEL Christine
,
Dr DALSTEIN Véronique
,
Pr POLETTE Myriam
,
Pr PRETET Jean-Luc
Tous les auteurs :
Lefevre M, Rousseau A, Rayon T, Dalstein V, Clavel C, Beby-Defaux A, Pretet JL, Soussan P, Polette M, Lacau Saint Guily J, Birembaut P,
Lien Pubmed
Résumé
Human Papillomavirus (HPV) infection is recognised as aetiological factor of carcinogenesis in oropharyngeal squamous cell carcinomas (OPC). HPV-related OPC respond better to treatments and have a significantly favourable outcome. Epithelial to mesenchymal transition (EMT) implicated in tumour invasion, is a hallmark of a poor prognosis in carcinomas.
Mots clés
Adult, Aged, Biomarkers, Tumor, analysis, Carcinoma, Squamous Cell, complications, DNA, Viral, analysis, Disease-Free Survival, Epithelial-Mesenchymal Transition, physiology, Female, Humans, Male, Middle Aged, Oropharyngeal Neoplasms, complications, Papillomaviridae, genetics, Papillomavirus Infections, complications, Prognosis
Référence
Br. J. Cancer. 2017 Jan;116(3):362-369
