Site-specific somatic mutagenesis in the retinal pigment epithelium.

Date publication

mai 2002

Journal

Investigative ophthalmology & visual science

Auteurs

Membres identifiés du Cancéropôle Est :
Pr CHAMBON Pierre , Dr METZGER Daniel

Tous les auteurs :
Mori M, Metzger D, Garnier JM, Chambon P, Mark M

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/11980850

Résumé

Generate site-specific somatic mutations selectively in the retinal pigment epithelium (RPE) in mice.

Mots clés

Animals, DNA, metabolism, Embryo, Mammalian, Female, Hybrid Cells, In Situ Hybridization, Integrases, genetics, Male, Membrane Glycoproteins, Mice, Mice, Transgenic, Mutagenesis, Site-Directed, Oxidoreductases, Pigment Epithelium of Eye, enzymology, Polymerase Chain Reaction, Proteins, genetics, Receptors, Retinoic Acid, genetics, Recombinant Fusion Proteins, genetics, Retinoid X Receptors, Transcription Factors, genetics, Viral Proteins, genetics

Référence

Invest. Ophthalmol. Vis. Sci.. 2002 May;43(5):1384-8