Are high- and low-molecular-weight sensitizing agents associated with different clinical phenotypes of occupational asthma?

Date publication

juin 2018

Journal

Allergy

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MEYER Nicolas

Tous les auteurs :
Vandenplas O, Godet J, Hurdubaea L, Rifflart C, Suojalehto H, Wiszniewska M, Munoz X, Sastre J, Klusackova P, Moore V, Merget R, Talini D, Svanes C, Mason P, dell'Omo M, Cullinan P, Moscato G, Quirce S, Hoyle J, Sherson D, Kauppi P, Preisser A, Meyer N, de Blay F,

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29956349

Résumé

High-molecular-weight (HMW) proteins and low-molecular-weight (LMW) chemicals can cause occupational asthma (OA) although few studies have thoroughly compared the clinical, physiological, and inflammatory patterns associated with these different types of agents. The aim of this study was to determine whether OA induced by HMW and LMW agents show distinct phenotypic profiles.

Mots clés

asthma, bronchial provocation tests, occupational diseases, phenotype

Référence

Allergy. 2018 Jun 28;: