A brief report of transformation from Non-small cell to small cell lung cancer: Molecular and therapeutic characteristics.

Fiche publication

Date publication

septembre 2018

Journal

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Auteurs

Membres identifiés du Cancéropôle Est :
Pr WESTEEL Virginie

Tous les auteurs :
Ferrer L, Giaj Levra M, Brevet M, Antoine M, Mazieres J, Rossi G, Chiari R, Westeel V, Poudenx M, Letreut J, Gervais R, Osman G, Girard N, Toffart AC, Novello S, Moro-Sibilot D

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/30217489

Résumé

Histological transformation from Non-small cell lung cancer (NSCLC) to SCLC is a mechanism of resistance in EGFR-mutant tumors but is also occasionally observed in non-mutated NSCLC.