Fiche publication
Date publication
août 2018
Journal
The European respiratory journal
Auteurs
Membres identifiés du Cancéropôle Est :
Pr QUANTIN Catherine
,
Pr BONNIAUD Philippe
,
Dr BELTRAMO Guillaume
Tous les auteurs :
Maitre T, Cottenet J, Beltramo G, Georges M, Blot M, Piroth L, Bonniaud P, Quantin C
Lien Pubmed
Résumé
An overall reduction in the incidence of AIDS and a change in the spectrum of lung disease have been noticed in persons living with the human immunodeficiency virus (PLHIV). Our aim was to provide an epidemiological update regarding the prevalence of lung diseases in PLHIV hospitalised in France. We analysed the prevalence of lung disease in PLHIV hospitalised in France from 2007 to 2013, from the French nationwide hospital medical information database, and assessed the association between HIV and incident non-infectious disease over 4 years of follow-up. A total of 52 091 PLHIV were hospitalised in France between 2007 and 2013. Among PLHIV hospitalised with lung disease, non-infectious lung diseases increased significantly from 45.6% to 54.7% between 2007 and 2013 whereas the proportion of patients with at least one infectious lung diseases decreased significantly. In 2010, 10 067 prevalent hospitalised PLHIV were compared with 8 244 682 hospitalised non-PLHIV. In 30-49-year-olds, HIV infection was associated with COPD, chronic respiratory failure, emphysema, lung fibrosis and PAH even after adjustment for smoking. The emergence of non-infectious lung disease in particular COPD, emphysema, lung fibrosis, PAH and chronic respiratory disease in PLHIV would justify mass screening in this population.
Référence
Eur. Respir. J.. 2018 Aug 23;:
