Fiche publication
Date publication
juillet 2018
Journal
Dalton transactions (Cambridge, England : 2003)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BETTAIEB Ali
,
Pr PAUL Catherine
,
Pr DENAT Franck
Tous les auteurs :
Pliquett J, Amor S, Ponce-Vargas M, Laly M, Racoeur C, Rousselin Y, Denat F, Bettaïeb A, Fleurat-Lessard P, Paul C, Goze C, Bodio E
Lien Pubmed
Résumé
A simple trifunctional BODIPY platform was designed. The high potential of this platform was validated via the elaboration of twelve optical theranostics. More specifically, we reported on the synthesis, the characterization, the photophysical properties, and the evaluation of the hydrophilicity properties of the different BODIPY derivatives, as well as a theoretical rationalization of the intriguing chemical behavior of some of them. The antiproliferative evaluation and confocal imaging of the different compounds in three human and murine cancer cell lines were performed and analysed, along with the measurement of gold(i) uptake in one cancer cell line via ICP-MS.
Référence
Dalton Trans. 2018 Jul 27;:
