Fiche publication


Date publication

juin 2018

Journal

Investigative ophthalmology & visual science

Auteurs

Membres identifiés du Cancéropôle Est :
Dr GARBAR Christian , Pr LABROUSSE Marc , Dr BOULAGNON-ROMBI Camille , Pr BENSUSSAN Armand


Tous les auteurs :
Henry A, Boulagnon-Rombi C, Menguy T, Giustiniani J, Garbar C, Mascaux C, Labrousse M, Milas C, Barbe C, Bensussan A, Durlach V, Arndt C

Résumé

Anti-angiogenic agents stand first in the treatment of neovascular diseases of the retina. CD160 appeared in several experimental studies as a marker of activated endothelial cells, suggesting it could represent a promising target for novel anti-angiogenic therapies. The aim of the present study was to assess the distribution of CD160 in the human eye, and to search for a possible correlation with retinal neovascular diseases.

Mots clés

Actins, metabolism, Aged, Antigens, CD, metabolism, Biomarkers, metabolism, Ciliary Body, metabolism, Conjunctiva, metabolism, Endoglin, metabolism, Endothelium, Vascular, metabolism, Epithelial Cells, metabolism, Female, GPI-Linked Proteins, metabolism, Humans, Macrophages, metabolism, Male, Middle Aged, Receptors, Immunologic, metabolism, Retinal Ganglion Cells, metabolism, Retinal Neovascularization, metabolism, Retinal Vessels, metabolism, Retrospective Studies, Tissue Donors, Transcriptional Regulator ERG, metabolism

Référence

Invest. Ophthalmol. Vis. Sci.. 2018 Jun 1;59(7):2679-2686