Effect of cumulative exposure to corticosteroid and DMARD on radiographic progression in rheumatoid arthritis: results from the ESPOIR cohort.

Date publication

mai 2018

Journal

Rheumatology (Oxford, England)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GUILLEMIN Francis

Tous les auteurs :
Louveau B, De Rycke Y, Lafourcade A, Saraux A, Guillemin F, Tubach F, Fautrel B, Hajage D

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29796624

Résumé

Several authors have tried to predict the risk of radiographic progression in RA according to baseline characteristics, considering exposure to treatment only as a binary variable (Treated: Yes/No). This study aims to model the risk of 5-year radiographic progression taking into account both baseline characteristics and the cumulative time-varying exposure to corticosteroids or DMARDs.

Mots clés

Administration, Oral, Adolescent, Adult, Aged, Antirheumatic Agents, administration & dosage, Arthritis, Rheumatoid, diagnosis, Disease Progression, Dose-Response Relationship, Drug, Female, Follow-Up Studies, Forecasting, Glucocorticoids, administration & dosage, Humans, Joints, diagnostic imaging, Male, Middle Aged, Radiography, methods, Retrospective Studies, Young Adult

Référence

Rheumatology (Oxford). 2018 May 22;: