Fiche publication
Date publication
mai 2018
Journal
Atherosclerosis
Auteurs
Membres identifiés du Cancéropôle Est :
Dr LAGROST Laurent
,
Dr PAIS DE BARROS Jean-Paul
,
Dr QUERE Ronan
Tous les auteurs :
Thomas C, Jalil A, Magnani C, Ishibashi M, Queré R, Bourgeois T, Bergas V, Ménégaut L, Patoli D, Le Guern N, Labbé J, Gautier T, de Barros JPP, Lagrost L, Masson D
Lien Pubmed
Résumé
LPCAT3 plays a major role in phospholipid metabolism in the liver and intestine. However, the impact of LPCAT3 on hematopoietic cell and macrophage functions has yet to be described. Our aim was to understand the functions of LPCAT3 in macrophages and to investigate whether LPCAT3 deficiency in hematopoietic cells may affect atherosclerosis development.
Mots clés
Arachidonic acid, Atherosclerosis, Cholesterol efflux, Macrophage, Phospholipid
Référence
Atherosclerosis. 2018 May 18;:
