Fiche publication


Date publication

avril 2018

Journal

EBioMedicine

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ADOTEVI Olivier , Pr HERBEIN Georges


Tous les auteurs :
Kumar A, Tripathy MK, Pasquereau S, Al Moussawi F, Abbas W, Coquard L, Khan KA, Russo L, Algros MP, Valmary-Degano S, Adotevi O, Morot-Bizot S, Herbein G

Résumé

Human cytomegalovirus (HCMV) establishes a persistent life-long infection and increasing evidence indicates HCMV infection can modulate signaling pathways associated with oncogenesis. Breast milk is an important route of HCMV transmission in humans and we hypothesized that mammary epithelial cells could be one of the main cellular targets of HCMV infection.

Mots clés

CTH cells, Cytomegalovirus, HCMV, HCMV-DB, HMECs, Oncogenesis, Transformation, lncRNA4.9

Référence

EBioMedicine. 2018 Apr;30:167-183