Fiche publication
Date publication
septembre 2018
Journal
Gynecologie, obstetrique, fertilite & senologie
Auteurs
Membres identifiés du Cancéropôle Est :
Dr LUPORSI Elisabeth
,
Pr MATHELIN Carole
Tous les auteurs :
Piffer A, Luporsi E, Mathelin C
Lien Pubmed
Résumé
About 5% of breast cancers are linked to an inherited predisposition, the two most known susceptibility genes being BRCA1 and BRCA2. Recently, new susceptibility genes, including PALB2, have been identified. The risk of breast cancer associated with a deleterious mutation of PALB2, the age of onset of these cancers, their prognosis and associated cancers have so far been the subject of controversy. Our objective was to clarify these different questions from an updated review of the literature.
Mots clés
Breast cancer, Cancer du sein, Mutation, Oncogenetics, Oncogénétique, PALB2
Référence
Gynecol Obstet Fertil Senol. 2018 Sep 19;:
