A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice.

Date publication

mai 2018

Journal

Investigative ophthalmology & visual science

Auteurs

Membres identifiés du Cancéropôle Est :
Dr HERAULT Yann

Tous les auteurs :
Moore BA, Roux MJ, Sebbag L, Cooper A, Edwards SG, Leonard BC, Imai DM, Griffey S, Bower L, Clary D, Lloyd KCK, Hérault Y, Thomasy SM, Murphy CJ, Moshiri A

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29847629

Résumé

The purpose of this study was to quantify the frequency and severity of ocular abnormalities affecting wild-type C57BL/6N mice, the most common strain used worldwide for the creation of single-gene knockouts.

Mots clés

Animals, Anterior Eye Segment, pathology, DNA, genetics, DNA Mutational Analysis, Disease Models, Animal, Eye Abnormalities, diagnosis, Intraocular Pressure, physiology, Male, Mice, Mice, Inbred C57BL, Mutation, Nuclear Proteins, genetics, Ophthalmoscopy, Posterior Eye Segment, pathology, Tomography, Optical Coherence

Référence

Invest. Ophthalmol. Vis. Sci.. 2018 May 1;59(6):2252-2261