Fiche publication
Date publication
avril 2016
Journal
Journal of colloid and interface science
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BOIREAU Wilfrid
,
Pr ROUX Stéphane
,
Dr ELIE-CAILLE Céline
Tous les auteurs :
Houmed Adabo A, Zeggari R, Mohamed Saïd N, Bazzi R, Elie-Caille C, Marquette C, Martini M, Tillement O, Perriat P, Chaix C, Boireau W, Roux S
Lien Pubmed
Résumé
Since it was demonstrated that nanostructured surfaces are more efficient for the detection based on the specific capture of analytes, there is a real need to develop strategies for grafting nanoparticles onto flat surfaces. Among the different routes for the functionalization of a surface, the reduction of diazonium salts appears very attractive for the covalent immobilization of nanoparticles because this method does not require a pre-treatment of the surface. For achieving this goal, gold nanoparticles coated by precursor of diazonium salts were synthesized by reduction of gold salt in presence of mercaptoaniline. These mercaptoaniline-coated gold nanoparticles (Au@MA) were successfully immobilized onto various conducting substrates (indium tin oxide (ITO), glassy carbon (GC) and gold electrodes with flat terraces) after addition of sodium nitrite at fixed potential. When applied onto the gold electrodes, such a grafting strategy led to an obvious enhancement of the luminescence of luminol used for the biodetection.
Mots clés
Diazonium Compounds, chemical synthesis, Electrochemical Techniques, Electrodes, Gold, chemistry, Hydrogen-Ion Concentration, Luminescence, Luminescent Measurements, methods, Metal Nanoparticles, chemistry, Organogold Compounds, analysis, Particle Size, Surface Properties
Référence
J Colloid Interface Sci. 2016 Apr;467:271-9
