Identification of novel recurrent ETV6-IgH fusions in primary central nervous system lymphoma.

Date publication

juillet 2018

Journal

Neuro-oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GAUCHOTTE Guillaume

Tous les auteurs :
Bruno A, Labreche K, Daniau M, Boisselier B, Gauchotte G, Royer-Perron L, Rahimian A, Lemoine F, de la Grange P, Guégan J, Bielle F, Polivka M, Adam C, Meyronet D, Figarella-Branger D, Villa C, Chrétien F, Eimer S, Davi F, Rousseau A, Houillier C, Soussain C, Mokhtari K, Hoang-Xuan K, Alentorn A

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29432597

Résumé

Primary central nervous system lymphoma (PCNSL) represents a particular entity within non-Hodgkin lymphomas and is associated with poor outcome. The present study addresses the potential clinical relevance of chimeric transcripts in PCNSL discovered by using RNA sequencing (RNA-seq).

Référence

Neuro-oncology. 2018 Jul 5;20(8):1092-1100