Neuromuscular Blocking Agents induced anaphylaxis: Results and trends of a French Pharmacovigilance survey from 2000 to 2012.

Date publication

avril 2018

Journal

Allergy

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GILLET Pierre

Tous les auteurs :
Petitpain N, Argoullon L, Masmoudi K, Fedrizzi S, Cottin J, Latarche C, Mertes PM, Gillet P,

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29654608

Résumé

Perioperative anaphylaxis mainly involves neuromuscular blocking agents (NMBAs) with an IgE mediated mechanism. In France, this life threatening condition is fairly reported by anesthetists and allergologists, and two safety alerts concerning suxamethonium were raised in 2011 and 2012. This led to start a national survey over the 2000-2012 period which objectives were to provide a descriptive analysis, to estimate incidence rates and to analyze the trends over this period.

Mots clés

Incidence, anaphylaxis, neuromuscular blocking agents, rocuronium, suxamethonium

Référence

Allergy. 2018 Apr 13;: