Fiche publication


Date publication

avril 2018

Journal

European journal of cancer (Oxford, England : 1990)

Auteurs

Membres identifiés du Cancéropôle Est :
Dr EYMARD Jean-Christophe , Dr SPAETH Dominique


Tous les auteurs :
Thibault C, Eymard JC, Birtle A, Krainer M, Baciarello G, Fléchon A, Le Moulec S, Spaeth D, Laguerre B, Caffo O, Deville JL, Beuzeboc P, Hasbini A, Gross-Goupil M, Helissey C, Bennamoun M, Hardy-Bessard AC, Oudard S

Résumé

Treatment option in patients with metastatic castration-resistant prostate cancer (mCRPC) previously treated with docetaxel (DOC), cabazitaxel (CABA) and new hormone therapy (NHT) is limited. Rechallenge with DOC is limited because of cumulative toxicities. This study investigated the activity and safety of CABA rechallenge in mCRPC.

Mots clés

Cabazitaxel, Metastatic castration-resistant prostate cancer, Overall survival, Progression-free survival, Rechallenge, Safety, Taxanes

Référence

Eur. J. Cancer. 2018 Apr 7;: