O-(2-(18)F-fluoroethyl)-l-tyrosine ((18)F-FET) uptake in insulinoma: first results from a xenograft mouse model and from human.

Fiche publication

Date publication

juillet 2017

Journal

Nuclear medicine and biology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BACHELLIER Philippe , Dr BRASSE David , Pr LAQUERRIERE Patrice , Pr NAMER Izzie-Jacques

Tous les auteurs :
Imperiale A, Boisson F, Kreutter G, Goichot B, Namer IJ, Bachellier P, Laquerriere P, Kessler L, Marchand P, Brasse D

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/28793277

Résumé

Herein we have evaluated the uptake of O-(2-(18)F-fluoroethyl)-l-tyrosine ((18)F-FET) in insulinoma in comparison with those of 6-(18)F-fluoro-3,4-dihydroxy-l-phenylalanine ((18)F-FDOPA) providing first data from both murine xenograft model and one patient with proved endogenous hyperinsulinemic hypoglycemia.