Fiche publication
Date publication
février 2017
Journal
Sleep medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques
Tous les auteurs :
Ruppert E, Bataillard M, Namer IJ, Tatu L, Hacquard A, Hugueny L, Hubbard J, Kilic-Huck U, Wolff V, Bourgin P
Lien Pubmed
Résumé
The pathophysiology of restless legs syndrome (RLS) involves a dopaminergic dysregulation that remains poorly understood, with controversial data from the literature. Stroke-related RLS is a rare condition that involves primarily the basal ganglia, the paramedian pons, and the thalamus. Given these elements, we studied dopaminergic metabolism in patients with RLS secondary to lenticulostriate infarction using structural and nuclear imaging in the striatum ipsilateral to the infarction area, as compared to the contralateral side. We hypothesized that dopaminergic metabolism would be impaired in the striatum ipsilateral to stroke.
Mots clés
Basal ganglia, Caudate nucleus, Dopamine dysregulation, Post stroke RLS, RLS pathophysiology, Restless legs syndrome
Référence
Sleep Med.. 2017 Feb;30:136-138
