Fiche publication


Date publication

octobre 2016

Journal

Clinical nuclear medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques , Pr FORNECKER Luc-Matthieu


Tous les auteurs :
De Marini P, Laplace A, Matuszak J, Fornecker LM, Namer IJ

Résumé

A 21-year-old man, allogeneic hematopoietic stem cell transplantation recipient, was referred to our nuclear medicine department for a suspicion of knee osteonecrosis. Bone scan with Tc-HMDP did not show abnormal bone uptake but an intense spleen accumulation. F-FDG PET/CT performed on the same day showed no pathological spleen uptake. The patient had secondary hemochromatosis resulting from frequent transfusions in the setting of a chronic graft versus host disease with hemolysis and thrombocytopenia. The last RBC and platelet transfusions were performed 9 and 2 days before the examination, respectively. Secondary hemochromatosis and recent transfusions may explain our findings.

Mots clés

Bone and Bones, diagnostic imaging, Erythrocyte Transfusion, adverse effects, Fluorodeoxyglucose F18, Graft vs Host Disease, diagnostic imaging, Hematopoietic Stem Cell Transplantation, adverse effects, Humans, Male, Platelet Transfusion, adverse effects, Positron Emission Tomography Computed Tomography, Radiopharmaceuticals, Spleen, diagnostic imaging, Technetium Tc 99m Medronate, analogs & derivatives, Young Adult

Référence

Clin Nucl Med. 2016 Oct;41(10):802-3