Fiche publication


Date publication

août 2016

Journal

Surgery

Auteurs

Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques


Tous les auteurs :
Battini S, Imperiale A, Taïeb D, Elbayed K, Cicek AE, Sebag F, Brunaud L, Namer IJ

Résumé

Primary hyperparathyroidism (PHPT) may be related to a single gland disease or multiglandular disease, which requires specific treatments. At present, an operation is the only curative treatment for PHPT. Currently, there are no biomarkers available to identify these 2 entities (single vs. multiple gland disease). The aims of the present study were to compare (1) the tissue metabolomics profiles between PHPT and renal hyperparathyroidism (secondary and tertiary) and (2) single gland disease with multiglandular disease in PHPT using metabolomics analysis.

Mots clés

Adult, Aged, Female, Humans, Hyperparathyroidism, Primary, diagnosis, Hyperparathyroidism, Secondary, diagnosis, Magnetic Resonance Spectroscopy, Male, Metabolomics, Middle Aged, Predictive Value of Tests, Reproducibility of Results, Retrospective Studies

Référence

Surgery. 2016 Aug;160(2):384-94