Fiche publication


Date publication

septembre 2015

Journal

Clinical nuclear medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques


Tous les auteurs :
Morland D, Wolff V, Blondet C, Marescaux C, Namer IJ

Résumé

We present the case of a 40-year-old man consulting for uncontrollable episodes of laughing related to emotional lability and not systematically linked to feelings of happiness. Seven months earlier he had presented a pontine ischemic stroke related to an occlusion of the basilar and left vertebral arteries. No epileptic activity or new MRI brain lesions were found. Brain perfusion SPECT performed showed marked hypoperfusion in the right frontal inferior and temporoinsular regions, suggesting a diaschisis phenomenon caused by pontine lesions and highlighted laughing regulation pathways. The patient was successfully treated with a serotonergic reuptake inhibitor, fluoxetine.

Mots clés

Adult, Affective Symptoms, diagnostic imaging, Humans, Laughter, Male, Pons, diagnostic imaging, Stroke, complications, Tomography, Emission-Computed, Single-Photon

Référence

Clin Nucl Med. 2015 Sep;40(9):734-6