Sucrose octasulfate dressing versus control dressing in patients with neuroischaemic diabetic foot ulcers (Explorer): an international, multicentre, double-blind, randomised, controlled trial.

Date publication

mars 2018

Journal

The lancet. Diabetes & endocrinology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PETIT Jean-Michel

Tous les auteurs :
Edmonds M, Lázaro-Martínez JL, Alfayate-García JM, Martini J, Petit JM, Rayman G, Lobmann R, Uccioli L, Sauvadet A, Bohbot S, Kerihuel JC, Piaggesi A

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29275068

Résumé

Diabetic foot ulcers are serious and challenging wounds associated with high risk of infection and lower-limb amputation. Ulcers are deemed neuroischaemic if peripheral neuropathy and peripheral artery disease are both present. No satisfactory treatment for neuroischaemic ulcers currently exists, and no evidence supports one particular dressing. We aimed to assess the effect of a sucrose octasulfate dressing versus a control dressing on wound closure in patients with neuroischaemic diabetic foot ulcers.

Mots clés

Aged, Anti-Ulcer Agents, administration & dosage, Bandages, Diabetic Foot, therapy, Diabetic Neuropathies, therapy, Double-Blind Method, Female, Humans, International Agencies, Ischemia, therapy, Male, Prognosis, Sucrose, administration & dosage

Référence

Lancet Diabetes Endocrinol. 2018 03;6(3):186-196