Static and dynamic F-FET PET for the characterization of gliomas defined by IDH and 1p/19q status.

Date publication

mars 2018

Journal

European journal of nuclear medicine and molecular imaging

Auteurs

Membres identifiés du Cancéropôle Est :
Pr VERGER Antoine

Tous les auteurs :
Verger A, Stoffels G, Bauer EK, Lohmann P, Blau T, Fink GR, Neumaier B, Shah NJ, Langen KJ, Galldiks N

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29043400

Résumé

The molecular features isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion have gained major importance for both glioma typing and prognosis and have, therefore, been integrated in the World Health Organization (WHO) classification in 2016. The aim of this study was to characterize static and dynamic O-(2-F-fluoroethyl)-L-tyrosine (F-FET) PET parameters in gliomas with or without IDH mutation or 1p/19q co-deletion.

Mots clés

1p/19q co-deletion, FET pet, Glioma, IDH mutation

Référence

Eur. J. Nucl. Med. Mol. Imaging. 2018 03;45(3):443-451