Evaluation of the new restandardized 25-hydroxyvitamin D assay on the iSYS platform.

Date publication

février 2018

Journal

Clinical biochemistry

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DUVILLARD Laurence

Tous les auteurs :
Denimal D, Roux S, Duvillard L

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29174995

Résumé

25-hydroxyvitamin D [25(OH)D] is the most reliable biomarker of vitamin D status, but until now 25(OH)D assays have suffered from inter-laboratory and inter-assay discrepancies. In the setting of the international Vitamin D Standardization Program, Immunodiagnostic Systems (IDS) recently reformulated and restandardized the 25(OH)D immunoassay available on the automated iSYS platform. In the present study, we evaluated this new generation of the 25(OH)D immunoassay (IS-2500).

Mots clés

Biological Assay, methods, Calibration, Chromatography, Liquid, methods, Clinical Laboratory Services, Humans, Immunoassay, methods, Laboratories, Reference Standards, Reproducibility of Results, Sensitivity and Specificity, Tandem Mass Spectrometry, methods, Vitamin D, analogs & derivatives

Référence

Clin. Biochem.. 2018 Feb;52:156-160