Genes and Pathways Regulated by Androgens in Human Neural Cells, Potential Candidates for the Male Excess in Autism Spectrum Disorder.

Date publication

janvier 2018

Journal

Biological psychiatry

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MANDEL Jean-Louis

Tous les auteurs :
Quartier A, Chatrousse L, Redin C, Keime C, Haumesser N, Maglott-Roth A, Brino L, Le Gras S, Benchoua A, Mandel JL, Piton A

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29428674

Résumé

Prenatal exposure to androgens during brain development in male individuals may participate to increase their susceptibility to develop neurodevelopmental disorders such as autism spectrum disorder (ASD) and intellectual disability. However, little is known about the action of androgens in human neural cells.

Mots clés

Androgen receptor, Androgens, Autism spectrum disorder, Gene expression, Neural progenitor cells, Sex bias

Référence

Biol. Psychiatry. 2018 Jan 9;: