Global role for coactivator complexes in RNA polymerase II transcription.

Date publication

octobre 2018

Journal

Transcription

Auteurs

Membres identifiés du Cancéropôle Est :
Dr DEVYS Didier , Dr TORA Laszlo

Tous les auteurs :
Fischer V, Schumacher K, Tora L, Devys D

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/30299209

Résumé

SAGA and TFIID are related transcription complexes, which were proposed to alternatively deliver TBP at different promoter classes. Recent genome-wide studies in yeast revealed that both complexes are required for the transcription of a vast majority of genes by RNA polymerase II raising new questions about the role of coactivators.

Mots clés

RNA polymerase II, SAGA complex, TFIID complex, coactivator, nascent RNA

Référence

Transcription. 2018 Oct 9;:1-8