Fiche publication


Date publication

novembre 2018

Journal

Drug development and industrial pharmacy

Auteurs

Membres identifiés du Cancéropôle Est :
Dr DUBOIS-POT-SCHNEIDER Hélène , Dr HOULGATTE Rémy , Pr RIHN Bertrand


Tous les auteurs :
Safar R, Houlgatte R, Le Faou A, Ronzani C, Wu W, Ferrari L, Dubois-Pot-Schneider H, Rihn BH, Joubert O

Résumé

S-nitrosogluthatione (GSNO), a S-nitrosothiol, is a commonly used as nitric oxide (NO) donor. However, its half-life is too short for a direct therapeutic use. To protect and ensure a sustained release of NO, the encapsulation of GSNO into nanoparticles may be an interesting option.

Mots clés

-nitrosoglutathione, monocytes, nitric oxide, polymeric nanoparticles, transcriptome

Référence

Drug Dev Ind Pharm. 2018 Nov 17;:1-28