Plasma Renin Concentration is Associated with Hemodynamic Deficiency and Adverse Renal Outcome in Septic Shock.

Date publication

novembre 2018

Journal

Shock (Augusta, Ga.)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DUVILLARD Laurence

Tous les auteurs :
Nguyen M, Denimal D, Dargent A, Guinot PG, Duvillard L, Quenot JP, Bouhemad B

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/30407370

Résumé

In septic shock, both systemic vasodilatation and glomerular arteriole dilatation are responsible for the drop in glomerular filtration observed in early acute kidney injury. Angiotensin II has been showed to act on both mechanisms. Our objective was to evaluate the impact of renin angiotensin system activation, on hemodynamic deficiency and renal outcome in patient with septic shock and to assess whether urinary sodium could be a reliable test for high plasma renin concentration screening.

Référence

Shock. 2018 Nov 6;: