Modular laser-based endoluminal ablation of the gastrointestinal tract: in vivo dose-effect evaluation and predictive numerical model.

Date publication

novembre 2018

Journal

Surgical endoscopy

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MARESCAUX Jacques , Pr MUTTER Didier

Tous les auteurs :
Quero G, Saccomandi P, Kwak JM, Dallemagne B, Costamagna G, Marescaux J, Mutter D, Diana M

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/30456508

Résumé

Endoscopic submucosal dissection allows for "en bloc" removal of early gastrointestinal neoplasms. However, it is technically demanding and time-consuming. Alternatives could rely on energy-based techniques. We aimed to evaluate a predictive numerical model of thermal damage to preoperatively define optimal laser settings allowing for a controlled ablation down to the submucosa, and the ability of confocal endomicroscopy to provide damage information.

Mots clés

Confocal endomicroscopy, Early gastrointestinal cancer, Laser ablation, Preclinical study, Predictive numerical model

Référence

Surg Endosc. 2018 Nov 19;: